NFL Week 5 Overreactions
USAT’s Lorenzo Reyes breaks down the best games from NFL Week 5.
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The San Francisco 49ers and Tampa Bay Buccaneers play on Sunday, Oct. 12, at the Buccaneers’ Raymond James Stadium in a game on the NFL Week 6 schedule.
Which team will win the NFL Week 6 game?
Check out these NFL Week 6 picks and NFL Week 6 predictions for the game, which can be seen at 1:25 p.m. MST on CBS (stream with FUBO).
The Buccaneers are a 3-point favorite over the 49ers in NFL Week 6 odds for the game, courtesy of BetMGM Sportsbook.
Tampa Bay is -165 on the moneyline, while San Francisco is +140. The over/under (point total) is set at 47.5 points.
NFL Week 6 picks: Eagles at Giants | Broncos vs Jets | Rams at Ravens | Cowboys at Panthers | Cardinals at Colts | Seahawks at Jaguars | Chargers at Dolphins | Browns at Steelers | Patriots at Saints | Titans at Raiders | 49ers at Buccaneers | Bengals at Packers | Lions at Chiefs | Bills at Falcons | Bears at Commanders | The Republic’s score predictions
Watch 49ers at Buccaneers live on FUBO (free trial)
Jeremy Cluff writes: “Two 4-1 teams face off in perhaps the game of the week in the NFL. The 49ers had extra time to get ready for this game after beating the Los Angeles Rams on Thursday Night Football, but Baker Mayfield and Tampa Bay will pull off some more late-game magic to move to 5-1.”
Bookies.com: Bet the Buccaneers to cover vs 49ers
Bill Speros writes: “Jim and Troy take a ride on the Pirate Ship as the two 4-1 division leaders meet in what could be an NFC playoff preview. Baker Mayfield continues to ball. And the Bucs’ defense will keep Mac Jones or Brock Purdy from letting the game get out of hand.”
The site’s formula predicts that the 49ers will win the NFL Week 6 game against the Buccaneers.
ESPN: Buccaneers have a 51.1% chance to beat 49ers on Sunday
The site gives the 49ers a 48.5% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.
Dimers: Buccaneers 25, 49ers 23
It writes: “After extensive simulations, our model gives the 49ers a win probability of 42%, while the Buccaneers have a win probability of 58%.”
Sportsnaut: Tampa Bay Buccaneers 26, San Francisco 49ers 21
Matt Johnson writes: “The San Francisco 49ers could get Ricky Pearsall and Jauan Jennings back in Week 6, but the Tampa Bay Buccaneers simply look like the superior team right now. Tampa Bay can stifle Christian McCaffrey on the ground, especially against this 49ers’ offensive line, and it has the receivers to make plays against San Francisco’s secondary. The 49ers will make it a battle until the fourth quarter, but Baker Mayfield delivers again in the clutch for a victory.”
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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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