One of the top runners in the NFL will be featured when Christian McCaffrey and the San Francisco 49ers (5-3) visit the New York Giants (2-6) on Sunday, November 2, 2025.
In their most recent outing, the 49ers were knocked off by the Houston Texans 26-15. Mac Jones threw for 193 yards, with two touchdowns and one interception on 19-of-32 passing (59.4%) for the Niners in that matchup against the Texans. He also added two carries for 23 yards. McCaffrey rushed for 25 yards on eight carries (3.1 yards per carry), adding three receptions for 43 yards. Jauan Jennings hauled in four receptions for 45 yards (averaging 11.3 per catch) against the Texans.
The Giants’ last game was a 38-20 loss to the Philadelphia Eagles. Jaxson Dart threw for 193 yards for the G-Men against the Eagles, going 14-for-24 (58.3%) with one touchdown and no interceptions. He added six carries for 17 yards and one touchdown. Tyrone Tracy Jr. carried the ball 10 times for 39 yards (3.9 yards per attempt). In the passing game, he added two catches for 14 yards. Wan’Dale Robinson recorded 48 yards through the air after three catches (on four targets).
In the story below, we provide all the details you need to watch this matchup on TV.
49ers vs. Giants betting information
National Football League odds courtesy of BetMGM. Odds updated Friday at 7:33 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: 49ers (-2.5)Moneyline: 49ers (-155), Giants (+130)Total: 48.5 points
49ers betting insights
The 49ers have played eight games, posting four wins against the spread.The 49ers have covered the spread once this season when favored by 2.5 points or more (in two chances).49ers games this year have hit the over in 50% of opportunities (four times in eight games with a set point total).
Giants betting insights
The Giants are 4-4-0 against the spread this year.So far this year, the Giants have been installed as underdogs by a 2.5-point margin or more seven times and are 4-3 ATS in those matchups.Giants games this year have hit the over on four of eight set point totals (50%).
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49ers leaders
Jones: 1,597 PASS YDS / 266.2 YPG / 65.9% / 8 TD / 5 INTMcCaffrey: 140 CAR / 490 YDS / 61.3 YPG / 3 TD / 56 REC / 559 YDS / 69.9 YPG / 3 TDBrian Robinson Jr.: 36 CAR / 144 YDS / 18.0 YPG / 0 TD / 5 REC / 11 YDS / 1.4 YPG / 0 TDKendrick Bourne: 28 REC / 429 YDS / 61.3 YPG / 0 TDRicky Pearsall: 20 REC / 327 YDS / 81.8 YPG / 0 TDBryce Huff: 19 TKL / 6.0 TFL / 4.0 SACK / 1 PDDee Winters: 54 TKL / 4.0 TFL / 3 PDDeommodore Lenoir: 29 TKL / 3.0 TFL / 1 INT / 3 PD
Giants leaders
Dart (QB): 984 YDS (59.9%) / 8 TD / 3 INT / 195 RUSH YDS / 4 RUSH TD / 27.9 RUSH YPGWan’Dale Robinson (WR): 38 REC / 494 YDS / 2 TD / 61.8 YPGRussell Wilson (QB): 786 YDS (58.9%) / 3 TD / 3 INT / 94 RUSH YDS / 0 RUSH TD / 18.8 RUSH YPGTheo Johnson (TE): 23 REC / 212 YDS / 4 TD / 26.5 YPGBrian Burns (OLB): 38 TKL / 13.0 TFL / 10.0 SACKAndru Phillips (CB): 39 TKL / 4.0 TFL / 2 INT / 9 PDBobby Okereke (LB): 68 TKL / 0.0 TFL / 1.0 SACKPaulson Adebo (CB): 48 TKL / 1.0 TFL
49ers vs. Giants game info
Game day: Sunday, November 2, 2025Game time: 1 p.m. ETLocation: East Rutherford, New JerseyStadium: MetLife StadiumTV channel: CBSLive stream: Watch on Fubo! (Regional restrictions may apply)Live stream: Watch on Paramount+! (Regional restrictions may apply)
Watch San Francisco 49ers vs. New York Giants on Fubo! (Regional restrictions may apply)
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