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San Francisco vs. Gonzaga odds, picks and predictions

March 10, 2025
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San Francisco vs. Gonzaga odds, picks and predictions
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The San Francisco Dons (24-8) and the Gonzaga Bulldogs (23-8) meet Monday in a West Coast Conference semifinal game at the Orleans Arena in Las Vegas. Tip-off is scheduled for 11:30 p.m. ET (ESPN2). Let’s analyze FanDuel Sportsbook’s college basketball odds around the San Francisco vs. Gonzaga odds, and make our expert college basketball picks and predictions.

The Dons meet the Bulldogs looking to snap a 32-game losing streak in this series. San Francisco’s last win against Gonzaga was a 66-65 win at home on Feb. 18, 2012. The Zags lead the all-time series 76-22, and San Francisco is just 4-55 in 59 tries against Gonzaga coach Mark Few.

Gonzaga won 95-75 in Frisco on March 1 as a 9-point favorite in the regular-season finale, and it won 88-77 on Feb. 13 at the McCarthey Athletic Center. However, San Francisco covered as a 16-point underdog as the Over (153.5) cashed in that game in Spokane. USF guard Malik Thomas went for 25 points with 4 made 3-pointers, while Gonzaga F Graham Ike was good for 18 points with 13 rebounds and a blocked shot, while G Ryan Nembhard had 18 points with 13 assists and a pair of triples.

San Francisco posted an 86-75 win as a 6-point favorite in the quarterfinals over Washington State Sunday as the Over (152.5) cashed. USF is 7-2 ATS in the past 9 games, while the Over has hit in 3 in a row, and 5 of the past 7 games.

Gonzaga wrapped up the regular season with 7 wins in the final 8 games, while cashing in 4 of the final 5 outings. In fact, the Bulldogs might have finished the season with their best stretch of basketball since the out-of-conference portion of the schedule back in November.

– Rankings: USA TODAY Sports Men’s Basketball Coaches Poll

Stream select live college basketball games and full replays: Get ESPN+

San Francisco vs. Gonzaga odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:39 a.m. ET.

Moneyline (ML): San Francisco +810 (bet $100 to win $810) | Gonzaga -1450 (bet $1,450 to win $100)
Against the spread: San Francisco +14.5 (-110) | Gonzaga -14.5 (-110)
Over/Under (O/U): 155.5 (O: -115 | U: -105)

San Francisco vs. Gonzaga picks and predictions

Prediction

Gonzaga 85, San Francisco 78

Moneyline

Gonzaga (-1450) will cost you nearly 15 times your potential return, and that’s way too much risk for such a little amount of profit. Even though the Zags haven’t lost to San Francisco (+810) since 2012, this Dons team is pretty strong, and this might be the weakest Gonzaga side we’ve seen in decades.

PASS.

Against the spread

SAN FRANCISCO +14.5 (-110) is a strong play catching double digits in this tournament game.

The Dons might have the long losing streak to Gonzaga -14.5 (-110), but they’re worth a play. San Francisco covered a big number on the road against Gonzaga last month. Plus, the Zags are 5-10 ATS in the past 15 games as a double-digit favorite.

Over/Under

OVER 155.5 (-115) is a strong play in this WCC semifinal nightcap in Vegas.

The Over cashed in both regular-season meetings between these teams, with Gonzaga averaging 91.5 points in those 2 contests, and San Francisco averaging 76.0.

The Dons have cashed high in 3 in a row, while going 5-2 in the past 7 outings since Feb. 8.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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