The Cincinnati Reds and San Francisco Giants will meet on Opening Day at Great American Ball Park at 4:10 p.m. ET, with Hunter Greene and Logan Webb the starting pitchers.
The 8.6 strikeouts per nine innings put together by the Reds pitching staff last season ranked 15th in MLB. The Giants pitched to a 4.10 ERA last season, which ranked 19th in baseball.
Get ready for the Reds vs. Giants with everything you need to know ahead of Thursday’s baseball action, including viewing options.
Reds vs. Giants: live stream info, TV channel & game time
Game day: Thursday, March 27, 2025Game time: 4:10 p.m. ETLocation: Cincinnati, OhioStadium: Great American Ball ParkTV channel: FanDuel Sports NetworkLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)
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Reds vs. Giants odds & betting lines
Favorite: Reds (-110, bet $110 to win $100)Underdog: Giants (-110, bet $110 to win $100)Over/under: 7.5
MLB odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 9:08 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
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