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Giants at Twins odds, picks and predictions

May 10, 2025
inSport
Giants at Twins odds, picks and predictions
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The San Francisco Giants (24-15) visit the Minnesota Twins (19-20) in the second game of their 3-game series Saturday at Target Field. First pitch is scheduled for 7:15 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s MLB odds around the Giants vs. Twins odds and make our expert MLB picks and predictions for the best bets.

Season series: Twins lead 1-0.

San Francisco snapped a 2-game winning streak Friday with a 3-1 loss against Minnesota as a -111 road favorite. The Giants were held to just 3 hits in the loss while avoiding a shutout courtesy of a seventh inning solo home run from 3B Matt Chapman.

Minnesota has now won 6 games in a row after Friday’s win while covering as a +103 home underdog. All 3 of the Twins runs came from singles including a first inning RBI from DH Trevor Larnach who opened the scoring in the win.

Giants at Twins projected starters

RHP Logan Webb vs. RHP Joe Ryan

Webb (4-2, 2.61 ERA) makes his ninth start. He has a 1.20 WHIP, 2.4 BB/9 and 10.4 K/9 through 48 1/3 innings.

Last start: Win, 7 IP, 1 ER, 6 H, 2 BB, 6 K in a 9-3 home victory vs. Colorado Rockies SundayHome/road splits: 2-2, 4.18 ERA, 1.32 WHIP, 10.9 K/9 in 5 road GS and 2-0, 0.44 ERA, 1.03 WHIP, 9.7 K/9 in 3 home GSSaturday will be Webb’s first career appearance against the Twins

Ryan (2-2, 2.93 ERA) makes his eighth start. He has a 0.90 WHIP, 1.1 BB/9 and 10.6 K/9 through 40 innings.

Last start: No-decision, 6 IP, 1 ER, 4 H, 1 BB, 8 K in a 6-1 road loss against Boston Red Sox FridayCareer vs. Giants: 2-1, 3.31 ERA (16 1/3 IP, 6 ER), 1.35 WHIP, 9.9 K/9 in 3 starts

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Giants at Twins odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:50 a.m. ET.

Moneyline (ML): Giants -105 (bet $105 to win $100) | Twins -115 (bet $115 to win $100)Run line (RL)/Against the spread (ATS): Giants -1.5 (+165) | Twins +1.5 (-200)Over/Under (O/U): 7 (O: -118 | U: -102)

Giants at Twins picks and predictions

Prediction

Twins 3, Giants 2

BET TWINS (-115).

The Twins have been hot lately, winning 6 games in a row and scoring 5 or more runs in 4 of their last 5. They have won each of their last 4 at home while the Giants are just 2-4 over their last 6 games on the road. The Giants have scored 3 or fewer runs in 3 of their last 4 games overall.

PASS.

There is minimal value on the run line.

BET UNDER 7 (-102).

While both teams have capabilities of exploding on offense, this matchup features starters who have been extremely reliable on both sides.

The Giants have scored 3 or fewer runs in 3 of their last 4 and 4 of their last 5 on the road while allowing 3 or fewer runs in 5 of their last 7.

The Twins have allowed 2 or fewer runs in each of their last 4 games while scoring 4 or fewer runs in 6 of their last 10.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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